News

Ursodeoxycholic Acid (UDCA): Natural Bile Acid, Empowering New Directions in Liver and Gallbladder Health
2025/7/10

As the global concern for liver and gallbladder health continues to rise, natural bile acid-based ingredients are being used more and more
widely in the field of pharmaceuticals and nutraceuticals. Among them, Ursodeoxycholic Acid (UDCA), as a classic medicinal ingredient, is
receiving extensive attention from pharmaceutical companies and research institutions.

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What is Ursodeoxyursolic Acid?

Ursodeoxyursolic acid (UDCA) is a naturally occurring secondary bile acid found in bile, originally isolated from bear bile, and now mostly
produced by chemical synthesis or microbial fermentation.UDCA is a white or off-white crystalline powder, odorless and tasteless, soluble
in ethanol, slightly soluble in water.
Main Uses 
Ursodeoxyursolic acid is mainly used in the treatment of various diseases of the hepatobiliary system, and its core mechanisms of action include: 
Promote bile flow: improve cholestasis and reduce hepatocellular damage 
Dissolve gallstones: especially cholesterol gallstones 
Anti-inflammatory and immunomodulation: applicable to primary biliary cholangitis (PBC) and other immune liver diseases 
Improvement of liver function indexes: significantly reduce the level of liver enzymes, such as ALT, AST and so on.
Wide range of applications 
1. Pharmaceutical industry: 
As an active ingredient (API) for prescription drugs, used in the preparation of tablets, capsules and other oral preparations
2. Commonly used in the treatment of PBC, gallstones, hepatitis, cirrhosis, etc. 
Nutraceuticals (in some regions): 
In some countries/regions, UDCA has also been used in high-end nutraceuticals as a supportive ingredient for liver and gallbladder health. 
3. Scientific research and development of functional foods: 
More and more scientific research projects are focusing on the regulation mechanism of bile acid metabolism and microecology. More and
more scientific research projects focus on its regulation mechanism on bile acid metabolism and microecological balance.
With global consumers' increased concern for liver health, Ursodeoxycholic Acid (UDCA) is becoming one of the key ingredients of interest to
drug manufacturers and nutraceutical brand owners. Coupled with technological advances and regulatory policy support, the application
scenarios of UDCA are also expanding, with broad growth potential.
If you are interested in Ursodeoxycholic Acid, please contact us for product information, COA, MSDS and sample support.

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