News

Undenatured Collagen Type II for joint health

In recent years, a new functional raw material for joint care, Undenatured Collagen Type Ⅱ, has been 

favored for its unique mechanism of action and excellent joint care effect.

What is non-denatured Undenatured Collagen Type Ⅱ?

Undenatured Collagen Type Ⅱ, abbreviated as UCⅡ, is a non-denatured collagen made from animal cartilage.

It is based on animal cartilage as raw material, using low-temperature extraction technology, to obtain the 

complete retention of large molecules of collagen triple helix structure of collagen has not changed.

UC-II is mainly distributed in cartilage, vitreous humor, nucleus pulposus, cornea and embryonic epithelial cells, 

and possesses the basic biological functions of collagen, such as good biocompatibility, biodegradability and 

low immunogenicity. UC-II can promote cartilage repair and inhibit cartilage degradation.

What are the functions of Undenatured Collagen Type Ⅱ?

A number of studies at home and abroad have shown that daily supplementation of sufficient 

amount of UC-II can achieve the following effects:

1. immunomodulation, elimination of inflammation and pain relief;　　

2. improving the intra-articular environment and slowing down the degradation/loss/wear of cartilage matrix;　

3. promote repair and regeneration of articular cartilage;　

4. improve the structure of articular cartilage and enhance the toughness of cartilage;　

5. increase joint synovial fluid and enhance joint flexibility;　

6. improve the symptoms of osteoarthritis and rheumatoid arthritis;

7. promote long-term joint health

Our company can provide type II collagen specifications: 

hydrolyzed collagen 10%; 20%; 30% and Undenatured Collagen Type Ⅱ

The difference between non-denatured type II collagen and ordinary collagen?

Most of the type II collagen on the market at present belongs to denatured type II collagen, in its production 

process, the macromolecule collagen by high temperature, hydrolysis and other processes, the three or four

levels of structure has been completely destroyed, the average molecular weight of 10,000 daltons or less, its

biological activity has been greatly reduced. And Undenatured Collagen Type II is based on animal cartilage 

as raw material, using low-temperature extraction technology, to get the complete retention of large molecules

of collagen natural triple helix structure, unchanged collagen products, molecular weight of 300,000 daltons or so,

high biological activity.

UC-II is so good, how safe is it?

In 2009, the United States listed UC-II as a GRAS recognized safe ingredient.

In 2016, the National Health Commission approved that UC-II can be produced and operated as a general 

food product, which also proves the high safety of UC-II.